ArticleOpen AccessMetadata saja
2025•Artikel Penelitian dan Pengabdian
Henslowia frutescens is a semi-parasitic plant, although considered harmful, it has medicinal and cosmetic potential. This plant has secondary metabolite compounds, namely phenolic compounds, flavonoids, saponins, tannins, and steroids which have high antioxidant activity. The purpose of this study was to determine the sunscreen activity of the ethanol extract of Henslowia frutescens based on the in vitro SPF (Sun Protecting Factor) value and to determine its antioxidant activity. The research stages included sampling, sampling, maceration extraction with 95% ethanol, yield calculation, phytochemical screening, sunscreen activity test based on SPF value, and antioxidant activity test. Data analysis was carried out descriptively based on the measurement results processed according to the calculation formula. The results showed that the sunscreen activity of the ethanol extract of Henslowia frutescens based on the in vitro SPF value was 14.57 - 25.20 with moderate protection category. The antioxidant activity of the ethanol extract of Henslowia frutescens showed a very strong category with an IC value of 22.82 ± 1.33.
ArticleOpen AccessMetadata saja
2025•Artikel Penelitian dan Pengabdian
Pumpkin (Cucurbita moschata Duch) is a food rich in vitamin A, vitamin C, minerals, carbohydrates, and flavonoid compounds. Flavonoids have several pharmacological activities, including as antioxidants to ward off free radicals. This study aims to determine the total flavonoid content and antioxidant activity of pumpkin fruit. The extraction of pumpkin fruit was done by the maceration method in a 70% ethanol solvent. The total flavonoid test used the colorimetric method with a 10% AlCl3 reagent and quercetin as a positive control. Antioxidant activity was tested using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The results obtained for the total flavonoid content of the ethanol extract of pumpkin fruit amounted to 1.741 mgQE/g ± 0.2438 and an IC50 value of 379.44 ppm, including the category of weak antioxidant, compared with the positive control.
ArticleOpen AccessMetadata saja
2025•Artikel Penelitian dan Pengabdian
The Red Pidada (Sonneratia caseolaris L.) is one of the plants used in traditional ways, especially by Borneo's people, where the red Pidada leaves are used as a cool powder composition and applied to the face while doing activities under exposure to sunlight over a long time. Red Pidada extract has a very strong antioxidant activity of 21.62 ppm because it has secondary metabolite, which is a medicinal ingredients and have a strong molecular structure, and have various biological activities. Pidada redplant (Sonneratia caseolaris L.) is a mangrove that has antioxidant potential. Free radicals can cause cancer, heart disease, premature aging, and other degenerative diseases. The research objective was to determine the antioxidant activity of the Pidada red leaf extract and fraction.The research was conducted qualitatively and quantitatively. The qualitative test was carried out by the colour change test and the quantitative test using the ABTS method (2,2-azinobis-3-ethyl benzothiazolin-6-sulfonic acid) with a UV-Visspectrophotometer. Pidada redleaves were extracted and fractionated, namely ethanol extract, n-hexane fraction, ethyl acetate fraction, and ethanol fraction, and made inti various concentrations compared to vitamin C.The IC50 value determined the antioxidant activity. The results showed that the ethanol extract had an IC50 value of 1.32 ppm (very strong), n-hexanefraction of 19.89 ppm (very strong), ethylacetate fraction of 0.50 ppm (very strong), and ethanolfraction of 1.63 ppm (very strong).
ArticleOpen AccessMetadata saja
2024•Artikel Penelitian dan Pengabdian
East Kalimantan is one of the regions that cultivates red dragon fruit ( Hylocereus polyrhizus) in large quantities due to its promising health benefits. The peel of red dragon fruit has antioxidant activity comparable to its flesh, yet it is rarely utilized and often discarded as organic waste. This study aims to explore the potential of water and ethanol extracts from red dragon fruit peel as antioxidant sources that can serve as natural reducing and stabilizing agents in the biosynthesis of silver nanoparticles (AgNPs). Extraction using water and ethanol solvents was conducted to analyze the antioxidant compounds in the peel. The extract with the strongest antioxidant activity was used for AgNP biosynthesis, and the absorption peak was observed using UV-Vis spectrophotometry at a specific wavelength of 400–450 nm, which is characteristic of AgNP surface plasmon resonance. The results showed that the ethanol extract exhibited stronger antioxidant potential based on its lower IC₅₀ value and functioned effectively as a reducing and stabilizing agent at synthesis temperatures of 40–50°C, without degrading the extract's secondary metabolites. These findings support the utilization of red dragon fruit peel as a sustainable and eco-friendly raw material for the development of health-related products.
ThesisOpen AccessMetadata saja
2023•Skripsi, Thesis, Disertasi, dan Tugas Akhir
High exposure to free radicals on the skin can cause damage to skin cells or tissues. Damage to cells or tissues in the skin will result in the skin being susceptible to diseases such as autoimmunity, skin cancer, and premature aging. Antioxidants function to protect the body from free radicals, both internally and externally. The part of the body that is often exposed to free radicals externally is the skin, such as ultraviolet radiation and cigarette smoke. One of the plants that has the potential for antioxidant compounds is the seeds of passion fruit. Purple passion fruit seed extract contains flavonoids, tannins, saponins and triterpenoids which are secondary metabolites. The research method included sample preparation,determination, simplicia manufacture, sample extraction using methanol solvent, thickening process by maceration process, phytochemical screening, and testing of antioxidant activity using the DPPH (2,2diphenyl-1-picrylhydrazyl) method by UV-Vis spectrophotometry.
